GLP-1 medications such as Ozempic and Wegovy have significantly reshaped the weight loss market by improving blood sugar regulation, insulin sensitivity, and appetite control

Contact your GP or healthcare professional if you experience: Persistent vomiting lasting more than 2448 hours, particularly if you cannot keep down fluids Signs of dehydration including dark urine, dizziness, dry mouth, reduced urination, or feeling faint when standing Abdominal pain , especially if severe, constant or located in the upper abdomen radiating to the back Visual changes in vomit, such as blood (appearing red or resembling coffee grounds) Inability to take other essential medications due to vomiting Significant weight loss beyond expected therapeutic effects Symptoms of gallbladder disease including pain in the upper right abdomen, fever, or yellowing of the skin/eyes Symptoms of bowel obstruction such as abdominal distension, inability to pass stool or gas If your GP is unavailable, contact NHS 111 for advice

Functional MRI studies have shown that GLP-1 receptor agonists can reduce activation in brain reward centres when patients view images of high-calorie foods, suggesting a reduction in food cravings and reward-driven eating
Wilhite K et al
Semaglutide also comes in an oral version